Multi-component prime-boost Chlamydia trachomatis vaccination regimes induce antibody and T cell responses and accelerate clearance of infection in a non-human primate model

Multi-component prime-boost Chlamydia trachomatis vaccination regimes induce antibody and T cell responses and accelerate clearance of infection in a non-human primate model

It is of international priority to develop a vaccine against sexually transmitted Chlamydia trachomatis infections to combat the continued global spread of the infection. The optimal immunization strategy still remains to be fully elucidated. The aim of this study was to evaluate immunization strate...

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Bibliographic Details
Main Authors: Emma Lorenzen, Vanessa Contreras, Anja W. Olsen, Peter Andersen, Delphine Desjardins, Ida Rosenkrands, Helene Bæk Juel, Benoit Delache, Sebastien Langlois, Constance Delaugerre, Christophe Joubert, Nathalie Dereuddre-Bosquet, Cécile Bébéar, Bertille De Barbeyrac, Arabella Touati, Paul F. McKay, Robin J. Shattock, Roger Le Grand, Frank Follmann, Jes Dietrich
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
vaccine
infection
immunology
bacteria
CD4/CD8 lymphocytes
Chlamydia trachomatis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1057375/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1057375/full

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