Upregulation of Enhancer of Zeste Homolog 2 (EZH2) with Associated pERK Co-Expression and PRC2 Complex Protein SUZ12 Correlation in Adult T-Cell Leukemia/Lymphoma

EZH2, a subunit of the polycomb repressive complex 2 (PRC2), is an important methyltransferase that catalyzes the trimethylation of histone H3 at lysine 27 (H3K27me3). EZH2 is overexpressed in various malignancies. Here, we investigated EZH2 expression and potential signaling molecules that correlat...

Full description

Bibliographic Details
Main Authors: Jiani Chai, Jui Choudhuri, Jerald Z. Gong, Yanhua Wang, Xuejun Tian
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/16/3/646