Regulatory T cells expressing CD19-targeted chimeric antigen receptor restore homeostasis in Systemic Lupus Erythematosus

Regulatory T cells expressing CD19-targeted chimeric antigen receptor restore homeostasis in Systemic Lupus Erythematosus

Abstract Systemic Lupus Erythematosus (SLE) is a progressive disease leading to immune-mediated tissue damage, associated with an alteration of lymphoid organs. Therapeutic strategies involving regulatory T (Treg) lymphocytes, which physiologically quench autoimmunity and support long-term immune to...

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Bibliographic Details
Main Authors: M. Doglio, A. Ugolini, C. Bercher-Brayer, B. Camisa, C. Toma, R. Norata, S. Del Rosso, R. Greco, F. Ciceri, F. Sanvito, M. Casucci, A. A. Manfredi, C. Bonini
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46448-9

Internet

https://doi.org/10.1038/s41467-024-46448-9

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