Presence of protein production enhancers results in significantly higher methanol-induced protein production in Pichia pastoris

Abstract Background The yeast Komagataella phaffii, better known as Pichia pastoris, is a commonly used host for recombinant protein production. Here expression vectors are reported that address the different steps of the transcription–translation–secretion pathway of heterologous protein production...

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Bibliographic Details
Main Authors: Loknath Gidijala, Stefan Uthoff, Sebastiaan J. van Kampen, Alexander Steinbüchel, Raymond M. D. Verhaert
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-018-0961-4