Transcriptional Profiling Suggests T Cells Cluster around Neurons Injected with <named-content content-type="genus-species">Toxoplasma gondii</named-content> Proteins

Transcriptional Profiling Suggests T Cells Cluster around Neurons Injected with <named-content content-type="genus-species">Toxoplasma gondii</named-content> Proteins

ABSTRACT Toxoplasma gondii’s tropism for and persistence in the central nervous system (CNS) underlies the symptomatic disease that T. gondii causes in humans. Our recent work has shown that neurons are the primary CNS cell with which Toxoplasma interacts and which it infects in vivo. This predilect...

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Bibliographic Details
Main Authors: Emily F. Merritt, Hannah J. Johnson, Zhee Sheen Wong, Adam S. Buntzman, Austin C. Conklin, Carla M. Cabral, Casey E. Romanoski, Jon P. Boyle, Anita A. Koshy
Format: Article
Language:English
Published: American Society for Microbiology 2020-10-01
Series:mSphere
Subjects:
RNA-seq
Toxoplasma gondii
host-pathogen interactions
immunology
laser capture microdissection
neuroscience
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00538-20

Internet

https://journals.asm.org/doi/10.1128/mSphere.00538-20

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