PI3K-CCL2-CCR2-MDSCs axis: A potential pathway for tumor Clostridia-promoted CD 8+ T lymphocyte infiltration in bile tract cancers

Background: Most patients with resected bile tract cancers (BTCs) survive for less than 5 years; however, some achieve better prognosis. The tumor microbiome can improve survival by regulating the tumor immune microenvironment. However, whether the tumor microbiome promotes immune cell infiltration...

Full description

Bibliographic Details
Main Authors: Wen-Jie Ma, Zheng-Hua Li, Zhen-Ru Wu, Fei Liu, Jun-Ke Wang, Yu-Jun Shi, Yan-Wen Jin, Fu-Yu Li
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558623000453