PI3K-CCL2-CCR2-MDSCs axis: A potential pathway for tumor Clostridia-promoted CD 8+ T lymphocyte infiltration in bile tract cancers
Background: Most patients with resected bile tract cancers (BTCs) survive for less than 5 years; however, some achieve better prognosis. The tumor microbiome can improve survival by regulating the tumor immune microenvironment. However, whether the tumor microbiome promotes immune cell infiltration...
Main Authors: | Wen-Jie Ma, Zheng-Hua Li, Zhen-Ru Wu, Fei Liu, Jun-Ke Wang, Yu-Jun Shi, Yan-Wen Jin, Fu-Yu Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-09-01
|
Series: | Neoplasia: An International Journal for Oncology Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558623000453 |
Similar Items
-
Adipose Tissue-Derived CCL5 Enhances Local Pro-Inflammatory Monocytic MDSCs Accumulation and Inflammation via CCR5 Receptor in High-Fat Diet-Fed Mice
by: Pei-Chi Chan, et al.
Published: (2022-11-01) -
Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2+/CX3CR1+ M-MDSCs into the tumor microenvironment in a redundant manner
by: Gregory P. Takacs, et al.
Published: (2023-01-01) -
The Function and Therapeutic Implications of TNF Signaling in MDSCs
by: Kun Yu, et al.
Published: (2022-11-01) -
Immunotherapy of targeting MDSCs in tumor microenvironment
by: Hongshu Sui, et al.
Published: (2022-09-01) -
Research progress of MDSCs-targeted immunotherapy for pancreatic cancer
by: QIN Yahan, et al.
Published: (2023-10-01)