Astaxanthin Promotes Nrf2/ARE Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs

Oxidative stress is the main cause of diabetic nephropathy (DN) progression. Nuclear factor-erythroid 2-related factor 2 (Nrf2)/antioxidant response element (ARE) signaling is a crucial cellular defense system to cope with oxidative stress. Astaxanthin (AST) is a fat-soluble xanthophyll carotenoid w...

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Bibliographic Details
Main Authors: Qing Chen, Jun Tao, Xi Xie
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/16/4/117