Bifidobacterium affects antitumor efficacy of oncolytic adenovirus in a mouse model of melanoma

Bifidobacterium affects antitumor efficacy of oncolytic adenovirus in a mouse model of melanoma

Summary: Gut microbiota plays a key role in modulating responses to cancer immunotherapy in melanoma patients. Oncolytic viruses (OVs) represent emerging tools in cancer therapy, inducing a potent immunogenic cancer cell death (ICD) and recruiting immune cells in tumors, poorly infiltrated by T cell...

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Bibliographic Details
Main Authors: Lorella Tripodi, Sara Feola, Ilaria Granata, Thomas Whalley, Margherita Passariello, Cristian Capasso, Ludovica Coluccino, Maria Vitale, Giulia Scalia, Laura Gentile, Claudia De Lorenzo, Mario Rosario Guarracino, Giuseppe Castaldo, Valeria D’Argenio, Barbara Szomolay, Vincenzo Cerullo, Lucio Pastore
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Virology
Microbiome
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223017455

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http://www.sciencedirect.com/science/article/pii/S2589004223017455

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