Preventive consumption of green tea modifies the gut microbiota and provides persistent protection from high-fat diet-induced obesity
Green tea could reportedly modify gut microbiota and benefit on High-Fat-Diet (HFD) induced obesity. However, most of the studies usually gave green tea (GT) to animals while feeding them HFD. When thin or obese mice, drink GT continuously or only for a period of time, what kind of benefit will them...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-01-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464619305456 |
| _version_ | 1818950196739964928 |
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| author | Jing Zhu Ruitian Cai Yuxiang Tan Xiuqing Wu Qiong Wen Zonghua Liu Shu-Hua Ouyang Zhinan Yin Hengwen Yang |
| author_facet | Jing Zhu Ruitian Cai Yuxiang Tan Xiuqing Wu Qiong Wen Zonghua Liu Shu-Hua Ouyang Zhinan Yin Hengwen Yang |
| author_sort | Jing Zhu |
| collection | DOAJ |
| description | Green tea could reportedly modify gut microbiota and benefit on High-Fat-Diet (HFD) induced obesity. However, most of the studies usually gave green tea (GT) to animals while feeding them HFD. When thin or obese mice, drink GT continuously or only for a period of time, what kind of benefit will them get, is still need to evaluate. In this study, we found that preventive GT consumption by lean mice could prevent HFD-induced-obesity event after stop drinking GT, while the mice with pre-existing obesity couldn’t get such benefit. Gut microbiota structure analysis indicated that the anti-obesity effect by GT consumption always accompanied with microbiota structure modification. We hypothesized that this difference depended upon the status of gut microbiota. Therefore, to gain the persistently protective effect from GT, the precondition is drinking GT before getting fat; otherwise, GT could only slowdown the weight gain of the pre-obese mice by continuously consumption. |
| first_indexed | 2024-12-20T09:14:45Z |
| format | Article |
| id | doaj.art-8ecde9d183014b74b5130174ef5f5e41 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-20T09:14:45Z |
| publishDate | 2020-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-8ecde9d183014b74b5130174ef5f5e412022-12-21T19:45:28ZengElsevierJournal of Functional Foods1756-46462020-01-0164103621Preventive consumption of green tea modifies the gut microbiota and provides persistent protection from high-fat diet-induced obesityJing Zhu0Ruitian Cai1Yuxiang Tan2Xiuqing Wu3Qiong Wen4Zonghua Liu5Shu-Hua Ouyang6Zhinan Yin7Hengwen Yang8The Biomedical Translational Research Institute, Jinan University Faculty of Medical Science, Jinan University, Guangzhou, Guangdong 510632, PR China; Zhuhai Precision Medical Center, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Jinan University, Zhuhai, Guangdong 519000, PR ChinaThe Biomedical Translational Research Institute, Jinan University Faculty of Medical Science, Jinan University, Guangzhou, Guangdong 510632, PR China; Zhuhai Precision Medical Center, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Jinan University, Zhuhai, Guangdong 519000, PR ChinaThe Biomedical Translational Research Institute, Jinan University Faculty of Medical Science, Jinan University, Guangzhou, Guangdong 510632, PR China; Zhuhai Precision Medical Center, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Jinan University, Zhuhai, Guangdong 519000, PR ChinaThe Biomedical Translational Research Institute, Jinan University Faculty of Medical Science, Jinan University, Guangzhou, Guangdong 510632, PR China; Zhuhai Precision Medical Center, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Jinan University, Zhuhai, Guangdong 519000, PR ChinaThe Biomedical Translational Research Institute, Jinan University Faculty of Medical Science, Jinan University, Guangzhou, Guangdong 510632, PR China; Zhuhai Precision Medical Center, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Jinan University, Zhuhai, Guangdong 519000, PR ChinaThe Biomedical Translational Research Institute, Jinan University Faculty of Medical Science, Jinan University, Guangzhou, Guangdong 510632, PR China; Zhuhai Precision Medical Center, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Jinan University, Zhuhai, Guangdong 519000, PR ChinaAnti-Stress and Health Research Center, College of Pharmacy, Jinan University, Guangzhou, Guangdong 510632, PR ChinaThe Biomedical Translational Research Institute, Jinan University Faculty of Medical Science, Jinan University, Guangzhou, Guangdong 510632, PR China; Zhuhai Precision Medical Center, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Jinan University, Zhuhai, Guangdong 519000, PR China; Corresponding authors at: The Biomedical Translational Research Institute, Jinan University Faculty of Medical Science, Jinan University, Guangzhou, Guangdong 510632, PR China.The Biomedical Translational Research Institute, Jinan University Faculty of Medical Science, Jinan University, Guangzhou, Guangdong 510632, PR China; Zhuhai Precision Medical Center, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Jinan University, Zhuhai, Guangdong 519000, PR China; Corresponding authors at: The Biomedical Translational Research Institute, Jinan University Faculty of Medical Science, Jinan University, Guangzhou, Guangdong 510632, PR China.Green tea could reportedly modify gut microbiota and benefit on High-Fat-Diet (HFD) induced obesity. However, most of the studies usually gave green tea (GT) to animals while feeding them HFD. When thin or obese mice, drink GT continuously or only for a period of time, what kind of benefit will them get, is still need to evaluate. In this study, we found that preventive GT consumption by lean mice could prevent HFD-induced-obesity event after stop drinking GT, while the mice with pre-existing obesity couldn’t get such benefit. Gut microbiota structure analysis indicated that the anti-obesity effect by GT consumption always accompanied with microbiota structure modification. We hypothesized that this difference depended upon the status of gut microbiota. Therefore, to gain the persistently protective effect from GT, the precondition is drinking GT before getting fat; otherwise, GT could only slowdown the weight gain of the pre-obese mice by continuously consumption.http://www.sciencedirect.com/science/article/pii/S1756464619305456Green teaGut microbiotaObesityPreventionHigh-fat-diet |
| spellingShingle | Jing Zhu Ruitian Cai Yuxiang Tan Xiuqing Wu Qiong Wen Zonghua Liu Shu-Hua Ouyang Zhinan Yin Hengwen Yang Preventive consumption of green tea modifies the gut microbiota and provides persistent protection from high-fat diet-induced obesity Journal of Functional Foods Green tea Gut microbiota Obesity Prevention High-fat-diet |
| title | Preventive consumption of green tea modifies the gut microbiota and provides persistent protection from high-fat diet-induced obesity |
| title_full | Preventive consumption of green tea modifies the gut microbiota and provides persistent protection from high-fat diet-induced obesity |
| title_fullStr | Preventive consumption of green tea modifies the gut microbiota and provides persistent protection from high-fat diet-induced obesity |
| title_full_unstemmed | Preventive consumption of green tea modifies the gut microbiota and provides persistent protection from high-fat diet-induced obesity |
| title_short | Preventive consumption of green tea modifies the gut microbiota and provides persistent protection from high-fat diet-induced obesity |
| title_sort | preventive consumption of green tea modifies the gut microbiota and provides persistent protection from high fat diet induced obesity |
| topic | Green tea Gut microbiota Obesity Prevention High-fat-diet |
| url | http://www.sciencedirect.com/science/article/pii/S1756464619305456 |
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