Moving beyond the mousetrap: current and emerging humanized mouse and rat models for investigating prevention and cure strategies against HIV infection and associated pathologies

Moving beyond the mousetrap: current and emerging humanized mouse and rat models for investigating prevention and cure strategies against HIV infection and associated pathologies

Abstract The development of safe and effective combination antiretroviral therapies for human immunodeficiency virus (HIV) infection over the past several decades has significantly reduced HIV-associated morbidity and mortality. Additionally, antiretroviral drugs have provided an effective means of...

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Bibliographic Details
Main Authors: Yash Agarwal, Cole Beatty, Shivkumar Biradar, Isabella Castronova, Sara Ho, Kevin Melody, Moses Turkle Bility
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Retrovirology
Subjects:
Humanized mouse and rat models
Modeling HIV infection and reservoir
Modeling human anti-HIV immune response
In vivo models for HIV cure
Animal models for HIV vaccines
Online Access:http://link.springer.com/article/10.1186/s12977-020-00515-3

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http://link.springer.com/article/10.1186/s12977-020-00515-3

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