SiNPs induce ferroptosis in HUVECs through p38 inhibiting NrF2 pathway

SiNPs induce ferroptosis in HUVECs through p38 inhibiting NrF2 pathway

IntroductionDespite of growing evidence linking silica nanoparticles (SiNPs), one of the global-top-three-produced and -used nanoparticle (NP), to human health risks, there remain many knowledge gaps over the adverse effects of SiNPs exposure on cardiovascular system and the underlying molecular mec...

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Bibliographic Details
Main Authors: Xiaojun Jiang, Huiqian Gao, Yunchang Cao, Shuting Chen, Fangfang Huang, Yashi Feng, Yuqi Zhang, Shaolong Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Public Health
Subjects:
ferroptosis
sillica nanoparticle (SiNP)
endothelial cell (EC)
p38
Nrf2
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2023.1024130/full

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https://www.frontiersin.org/articles/10.3389/fpubh.2023.1024130/full

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