Diagnostic biomarker kinetics: how brain-derived biomarkers distribute through the human body, and how this affects their diagnostic significance: the case of S100B

Abstract Blood biomarkers of neurological diseases are often employed to rule out or confirm the presence of significant intracranial or cerebrovascular pathology or for the differential diagnosis of conditions with similar presentations (e.g., hemorrhagic vs. embolic stroke). More widespread utiliz...

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Bibliographic Details
Main Authors: Robert Murcko, Nicola Marchi, Damian Bailey, Damir Janigro
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-022-00329-9