Drp1 Overexpression Decreases Insulin Content in Pancreatic MIN6 Cells

Drp1 Overexpression Decreases Insulin Content in Pancreatic MIN6 Cells

Mitochondrial dynamics and bioenergetics are central to glucose-stimulated insulin secretion by pancreatic beta cells. Previously, we demonstrated that a disturbance in glucose-invoked fission impairs insulin secretion by compromising glucose catabolism. Here, we investigated whether the overexpress...

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Bibliographic Details
Main Authors: Uma D. Kabra, Noah Moruzzi, Per-Olof Berggren, Martin Jastroch
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
dynamin-related protein 1
glucose-stimulated insulin secretion
insulin content
overexpression
MIN6 cell
bioenergetics
Online Access:https://www.mdpi.com/1422-0067/23/20/12338

Internet

https://www.mdpi.com/1422-0067/23/20/12338

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