Microbial Asymmetric Functionalization of β-Cyclocitral-Derived Tetramethyl-Substituted γ-Lactone

Microbial Asymmetric Functionalization of β-Cyclocitral-Derived Tetramethyl-Substituted γ-Lactone

Searching for the new anticancer compounds we prepared three new β-cyclocitral-derived hydroxyl-γ-lactones by microbial hydroxylation of tetramethyl-substituted bicyclic γ-lactone. The substrate was transformed by the enzymatic system of filamentous fungi. Three out of fif...

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Bibliographic Details
Main Authors: Marcelina Mazur, Witold Gładkowski, Aleksandra Pawlak, Bożena Obmińska-Mrukowicz, Gabriela Maciejewska, Czesław Wawrzeńczyk
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Molecules
Subjects:
asymmetric hydroxylation
antiproliferative activity
<i>Fusarium culmorum</i>
<i>Armillaria mellea</i>
<i>Trametes versicolor</i>
Online Access:https://www.mdpi.com/1420-3049/24/4/666

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https://www.mdpi.com/1420-3049/24/4/666

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