Microtubule disruption synergizes with STING signaling to show potent and broad-spectrum antiviral activity.

The activation of stimulator of interferon genes (STING) signaling induces the production of type I interferons (IFNs), which play critical roles in protective innate immunity for the host to defend against viral infections. Therefore, achieving sustained or enhanced STING activation could become an...

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Bibliographic Details
Main Authors: Jing Han, Zhimeng Wang, Fangping Han, Bo Peng, Juanjuan Du, Conggang Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-02-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1012048&type=printable