Over-stimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization: <it>lessons learnt from laron syndrome</it>
<p>Abstract</p> <p>The insulin/insulin-like growth factor-1 (IGF-1) pathway drives an evolutionarily conserved network that regulates lifespan and longevity. Individuals with Laron syndrome who carry mutations in the growth hormone receptor (<it>GHR</it>) gene that lead...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-06-01
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| Series: | Nutrition & Metabolism |
| Online Access: | http://www.nutritionandmetabolism.com/content/8/1/41 |