Klotho inversely relates with carotid intima- media thickness in atherosclerotic patients with normal renal function (eGFR ≥60 mL/min/1.73m2): a proof-of-concept study

Klotho inversely relates with carotid intima- media thickness in atherosclerotic patients with normal renal function (eGFR ≥60 mL/min/1.73m2): a proof-of-concept study

IntroductionKlotho protein is predominantly expressed in the kidneys and has also been detected in vascular tissue and peripheral blood circulating cells to a lesser extent. Carotid artery intima-media thickness (CIMT) burden, a marker of subclinical atherosclerosis, has been associated with reducti...

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Bibliographic Details
Main Authors: Javier Donate-Correa, Ernesto Martín-Núñez, Alberto Martin-Olivera, Carmen Mora-Fernández, Víctor G. Tagua, Carla M. Ferri, Ángel López-Castillo, Alejandro Delgado-Molinos, Victoria Castro López-Tarruella, Miguel A. Arévalo-Gómez, Nayra Pérez-Delgado, Ainhoa González-Luis, Juan F. Navarro-González
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Endocrinology
Subjects:
Klotho
carotid
intima and media thickness
gene expression data
serum
immunohistochemistry
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1146012/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1146012/full

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