Evaluation of factors influencing expression and extraction of recombinant bacteriophage endolysins in Escherichia coli

Abstract Background Endolysins are peptidoglycan hydrolases with promising use as environment-friendly antibacterials mainly when used topically. However, in general, endolysin expression is hampered by its low solubility. Thus, a critical point in endolysin industrial production is optimizing their...

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Bibliographic Details
Main Authors: Cecilia Lucía Balaban, Cristian Alejandro Suárez, Carina Andrea Boncompain, Natalia Peressutti-Bacci, Eduardo Augusto Ceccarelli, Héctor Ricardo Morbidoni
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Microbial Cell Factories
Subjects:
Online Access:https://doi.org/10.1186/s12934-022-01766-9