Microvascular Contributions to Alzheimer Disease Pathogenesis: Is Alzheimer Disease Primarily an Endotheliopathy?
Alzheimer disease (AD) models are based on the notion that abnormal protein aggregation is the primary event in AD, which begins a decade or longer prior to symptom onset, and culminates in neurodegeneration; however, emerging evidence from animal and clinical studies suggests that reduced blood flo...
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Format: | Article |
Language: | English |
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MDPI AG
2023-05-01
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Series: | Biomolecules |
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Online Access: | https://www.mdpi.com/2218-273X/13/5/830 |