Oral administration of cystine and theanine attenuates 5-fluorouracil-induced intestinal mucositis and diarrhea by suppressing both glutathione level decrease and ROS production in the small intestine of mucositis mouse model

Oral administration of cystine and theanine attenuates 5-fluorouracil-induced intestinal mucositis and diarrhea by suppressing both glutathione level decrease and ROS production in the small intestine of mucositis mouse model

Abstract Background Chemotherapy is frequently used in cancer treatment; however, it may cause adverse events, which must be managed. Reactive oxygen species (ROS) have been reported to be involved in the induction of intestinal mucositis and diarrhea, which are common side effects of treatment with...

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Bibliographic Details
Main Authors: Junya Yoneda, Sachiko Nishikawa, Shigekazu Kurihara
Format: Article
Language:English
Published: BMC 2021-12-01
Series:BMC Cancer
Subjects:
Mucositis
Chemotherapy
Adverse events
Diarrhea
Cancer
Cystine/Theanine
Online Access:https://doi.org/10.1186/s12885-021-09057-z

Internet

https://doi.org/10.1186/s12885-021-09057-z

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