The Effects of 1-<i>O</i>-Acetylbritannilactone Isolated from <i>Inula britannica</i> Flowers on Human Neutrophil Elastase and Inflammation of RAW 264.7 Cells and Zebrafish Larvae

The Effects of 1-<i>O</i>-Acetylbritannilactone Isolated from <i>Inula britannica</i> Flowers on Human Neutrophil Elastase and Inflammation of RAW 264.7 Cells and Zebrafish Larvae

During a search for natural inflammatory inhibitors, 1-<i>O</i>-acetylbritannilactone (ABL), a sesquiterpene lactone, was isolated from the flowers of <i>Inula britannica</i>. ABL significantly inhibited human neutrophil elastase (HNE) with a half-maximal inhibitory concentra...

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Bibliographic Details
Main Authors: Ik Soo Lee, Yu-Ri Lee, Jea Heon Sim, Ki Mo Kim, Young Sook Kim
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
<i>Inula britannica</i>
sesquiterpene lactone
human neutrophil elastase
RAW 264.7 cells
zebrafish
Online Access:https://www.mdpi.com/1420-3049/28/11/4320

Internet

https://www.mdpi.com/1420-3049/28/11/4320

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