Novel acyl carbamates and acyl / diacyl ureas show in vitro efficacy against Toxoplasma gondii and Cryptosporidium parvum

Toxoplasma gondii and Cryptosporidium parvum are protozoan parasites that are highly prevalent and opportunistically infect humans worldwide, but for which completely effective and safe medications are lacking. Herein, we synthesized a series of novel small molecules bearing the diacyl urea scaffold...

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Bibliographic Details
Main Authors: Kun Li, Gregory M. Grooms, Shahbaz M. Khan, Anolan Garcia Hernandez, William H. Witola, Jozef Stec
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320720300269