Enhancing NSCLC recurrence prediction with PET/CT habitat imaging, ctDNA, and integrative radiogenomics-blood insights

Enhancing NSCLC recurrence prediction with PET/CT habitat imaging, ctDNA, and integrative radiogenomics-blood insights

Abstract While we recognize the prognostic importance of clinicopathological measures and circulating tumor DNA (ctDNA), the independent contribution of quantitative image markers to prognosis in non-small cell lung cancer (NSCLC) remains underexplored. In our multi-institutional study of 394 NSCLC...

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Main Authors: Sheeba J. Sujit, Muhammad Aminu, Tatiana V. Karpinets, Pingjun Chen, Maliazurina B. Saad, Morteza Salehjahromi, John D. Boom, Mohamed Qayati, James M. George, Haley Allen, Mara B. Antonoff, Lingzhi Hong, Xin Hu, Simon Heeke, Hai T. Tran, Xiuning Le, Yasir Y. Elamin, Mehmet Altan, Natalie I. Vokes, Ajay Sheshadri, Julie Lin, Jianhua Zhang, Yang Lu, Carmen Behrens, Myrna C. B. Godoy, Carol C. Wu, Joe Y. Chang, Caroline Chung, David A. Jaffray, Ignacio I. Wistuba, J. Jack Lee, Ara A. Vaporciyan, Don L. Gibbons, John Heymach, Jianjun Zhang, Tina Cascone, Jia Wu
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-47512-0

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https://doi.org/10.1038/s41467-024-47512-0

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