The Interaction between Reactive Peritoneal Mesothelial Cells and Tumor Cells via Extracellular Vesicles Facilitates Colorectal Cancer Dissemination

The Interaction between Reactive Peritoneal Mesothelial Cells and Tumor Cells via Extracellular Vesicles Facilitates Colorectal Cancer Dissemination

Advanced colorectal cancer (CRC) is highly metastatic and often results in peritoneal dissemination. The extracellular vesicles (EVs) released by cancer cells in the microenvironment are important mediators of tumor metastasis. We investigated the contribution of EV-mediated interaction between peri...

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Bibliographic Details
Main Authors: Simona Serratì, Letizia Porcelli, Francesco Fragassi, Marianna Garofoli, Roberta Di Fonte, Livia Fucci, Rosa Maria Iacobazzi, Antonio Palazzo, Francesca Margheri, Grazia Cristiani, Anna Albano, Raffaele De Luca, Donato Francesco Altomare, Michele Simone, Amalia Azzariti
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
colorectal cancer
peritoneal carcinomatosis
CD44
mesothelial cells
MMT
Online Access:https://www.mdpi.com/2072-6694/13/10/2505

Internet

https://www.mdpi.com/2072-6694/13/10/2505

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