Small immunological clocks identified by deep learning and gradient boosting

BackgroundThe aging process affects all systems of the human body, and the observed increase in inflammatory components affecting the immune system in old age can lead to the development of age-associated diseases and systemic inflammation.ResultsWe propose a small clock model SImAge based on a limi...

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Bibliographic Details
Main Authors: Alena Kalyakulina, Igor Yusipov, Elena Kondakova, Maria Giulia Bacalini, Claudio Franceschi, Maria Vedunova, Mikhail Ivanchenko
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1177611/full