Designing a highly efficient type III polyketide whole-cell catalyst with minimized byproduct formation

Designing a highly efficient type III polyketide whole-cell catalyst with minimized byproduct formation

Abstract Background Polyketide synthases (PKSs) are classified into three types based on their enzyme structures. Among them, type III PKSs, catalyzing the iterative condensation of malonyl-coenzyme A (CoA) with a CoA-linked starter molecule, are important synthases of valuable natural products. How...

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Bibliographic Details
Main Authors: La Xiang, Xuanxuan Zhang, Yanyan Lei, Jieyuan Wu, Guangru Yan, Wei Chen, Shizhong Li, Wenzhao Wang, Jian-Ming Jin, Chaoning Liang, Shuang-Yan Tang
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Chalcone synthase
Byproduct
Growth selection
Naringenin
Type III polyketide
Online Access:https://doi.org/10.1186/s13068-024-02545-x

Internet

https://doi.org/10.1186/s13068-024-02545-x

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