Impact of Age and HIV Status on Immune Activation, Senescence and Apoptosis

Impact of Age and HIV Status on Immune Activation, Senescence and Apoptosis

IntroductionResidual immune dysfunctions, resembling those that occur during normal aging, may persist even in well-treated people with HIV (PWH), and accelerated aging has been proposed. We aimed to determine if HIV infection is an independent risk factor for T-cell immune dysfunctions including in...

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Bibliographic Details
Main Authors: Malene Hove-Skovsgaard, Yanan Zhao, Jeanette Linnea Tingstedt, Hans Jakob Hartling, Rebekka Faber Thudium, Thomas Benfield, Shoaib Afzal, Børge Nordestgaard, Henrik Ullum, Jan Gerstoft, Amanda Mocroft, Susanne Dam Nielsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
HIV infection
flow cytometry
T-cells
immune activation
immune senescence
aging
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.583569/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.583569/full

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