Live or Heat-Killed <i>Lactobacillus rhamnosus</i> Aerosolization Decreases Adenomatous Lung Cancer Development in a Mouse Carcinogen-Induced Tumor Model

Live or Heat-Killed <i>Lactobacillus rhamnosus</i> Aerosolization Decreases Adenomatous Lung Cancer Development in a Mouse Carcinogen-Induced Tumor Model

An immunosuppressive microenvironment in lung concurs to pre-malignant lesions progression to cancer. Here, we explore if perturbing lung microbiota, which contribute to immunosuppression, by antibiotics or probiotic aerosol interferes with lung cancer development in a mouse carcinogen-induced tumor...

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Bibliographic Details
Main Authors: Valentino Le Noci, Giancarla Bernardo, Giacomo Manenti, Gabriele Infante, Dariush Khaleghi Hashemian, Lucia Minoli, Simone Canesi, Francesca Bianchi, Tiziana Triulzi, Stefania Arioli, Loris De Cecco, Simone Guglielmetti, Federico Ambrogi, Camilla Recordati, Nicoletta Gagliano, Elda Tagliabue, Michele Sommariva, Lucia Sfondrini
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
carcinogenesis
lung cancer
lung microbiota
<i>Lactobacillus rhamnosus</i>
mouse models
tumor prevention
Online Access:https://www.mdpi.com/1422-0067/23/21/12748

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https://www.mdpi.com/1422-0067/23/21/12748

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