Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging

A plethora of factors have been attributed to underly aging, including oxidative stress, telomere shortening and cellular senescence. Several studies have shown a significant role of the cyclin-dependent kinase inhibitor p16ink4a in senescence and aging. However, its expression in development has be...

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Bibliographic Details
Main Authors: Hasan Safwan-Zaiter, Nicole Wagner, Jean-François Michiels, Kay-Dietrich Wagner
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/3/541