Novel Small Molecules with Anti-Inflammatory and Anti-Angiogenic Activity in a Mouse Model of Oxygen-Induced Retinopathy

Retinopathy of prematurity (ROP) has a dual-phase disease pathology; in phase 1, hyperoxia-induced vaso-obliteration occurs in the retinal vasculature due to increased oxidative stress (OS) and inflammation, followed by phase 2, where hypoxia increases the overproduction of growth factors, inducing...

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Bibliographic Details
Main Authors: Adam S. Dayoub, Eesha Acharya, Adnan Dibas, Harlan P. Jones, Suchismita Acharya
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/16/1371