Epigallocatechin gallate (EGCG) can epigenetically regulate the receptor of advanced glycation end products (RAGE) to ameliorate Osteoarthritis

Epigallocatechin gallate (EGCG) can epigenetically regulate the receptor of advanced glycation end products (RAGE) to ameliorate Osteoarthritis

Epigallocatechin-3-O-gallate is natural phytochemical of green tea. RAGE upregulation promotes osteoarthritis (OA) progression. Herein, we revealed that EGCG can repress RAGE expression epigenetically to ameliorate OA. Firstly we found that RAGE expression was dose-dependently reduced by EGCG on cho...

Full description

Bibliographic Details
Main Authors: Xiaoqing Wu, Xuanren Shi, Xiaoyong Chen, Zhanhai Yin
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Journal of Functional Foods
Subjects:
EGCG
RAGE
Osteoarthritis
DNA methylation
Epigenetic regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623002827

Internet

http://www.sciencedirect.com/science/article/pii/S1756464623002827

Similar Items