The Nucleoside/Nucleotide Analogs Tenofovir and Emtricitabine Are Inactive against SARS-CoV-2

The Nucleoside/Nucleotide Analogs Tenofovir and Emtricitabine Are Inactive against SARS-CoV-2

The urgent response to the COVID-19 pandemic required accelerated evaluation of many approved drugs as potential antiviral agents against the causative pathogen, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Using cell-based, biochemical, and modeling approaches, we studied the appro...

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Bibliographic Details
Main Authors: Joy Y. Feng, Venice Du Pont, Darius Babusis, Calvin J. Gordon, Egor P. Tchesnokov, Jason K. Perry, Vincent Duong, Arya Vijjapurapu, Xiaofeng Zhao, Julie Chan, Cal Cohen, Kavita Juneja, Tomas Cihlar, Matthias Götte, John P. Bilello
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
SARS-CoV-2
HIV-1 NRTI
tenofovir
TAF
TDF
FTC
Online Access:https://www.mdpi.com/1420-3049/27/13/4212

Internet

https://www.mdpi.com/1420-3049/27/13/4212

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