Mitochondrial Transplantation Attenuates Neural Damage and Improves Locomotor Function After Traumatic Spinal Cord Injury in Rats

Mitochondrial Transplantation Attenuates Neural Damage and Improves Locomotor Function After Traumatic Spinal Cord Injury in Rats

Mitochondrial dysfunction is a hallmark of secondary neuroinflammatory responses and neuronal death in spinal cord injury (SCI). Even though mitochondria-based therapy is an attractive therapeutic option for SCI, the efficacy of transplantation of allogeneic mitochondria in the treatment of SCI rema...

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Bibliographic Details
Main Authors: Ming-Wei Lin, Shih-Yuan Fang, Jung-Yu C. Hsu, Chih-Yuan Huang, Po-Hsuan Lee, Chi-Chen Huang, Hui-Fang Chen, Chen-Fuh Lam, Jung-Shun Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Neuroscience
Subjects:
allogenic mitochondria
mitochondrial dysfunction
mitochondrial transplantation
oxidative stress
spinal cord injury
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.800883/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.800883/full

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