The possible protective effect of the nuclear factor kappa B inhibitor pyrrolidine dithiocarbamate on tramadol-induced testicular damage in rats

Abstract Background Tramadol provokes oxidative stress that gives rise to apoptosis with alterations in the cellular structure and adversely influences male fertility. A specific inhibitor of nuclear factor kappa B (NF-κB), pyrrolidine dithiocarbamate (PDTC), has observable antioxidant and anti-infl...

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Bibliographic Details
Main Authors: Abeer Ramzy Hussieny Mahmoud, Suzan M. M. Moursi, Safya E. Esmaeel, Nesma Ismail Sharawy Mohamed, Nagah ElSayed Mohammed Ali
Format: Article
Language:English
Published: SpringerOpen 2023-06-01
Series:Egyptian Journal of Forensic Sciences
Subjects:
Online Access:https://doi.org/10.1186/s41935-023-00351-4