Gut Region-Specific Interleukin 1β Induction in Different Myenteric Neuronal Subpopulations of Type 1 Diabetic Rats

Gut Region-Specific Interleukin 1β Induction in Different Myenteric Neuronal Subpopulations of Type 1 Diabetic Rats

Interleukin 1β (IL1β) is a pro-inflammatory cytokine that may play a crucial role in enteric neuroinflammation in type 1 diabetes. Therefore, our goal is to evaluate the effects of chronic hyperglycemia and insulin treatment on IL1β immunoreactivity in myenteric neurons and their different subpopula...

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Bibliographic Details
Main Authors: Afnan AL Doghmi, Bence Pál Barta, Abigél Egyed-Kolumbán, Benita Onhausz, Szilvia Kiss, János Balázs, Zita Szalai, Mária Bagyánszki, Nikolett Bódi
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
interleukin 1β enteric nervous system
myenteric neurons
neuronal nitric oxide synthase
calcitonin gene-related peptide
type 1 diabetes
hyperglycemia
Online Access:https://www.mdpi.com/1422-0067/24/6/5804

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https://www.mdpi.com/1422-0067/24/6/5804

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