Targeting cyclin-dependent kinases in sarcoma treatment: Current perspectives and future directions

Targeting cyclin-dependent kinases in sarcoma treatment: Current perspectives and future directions

Effective treatment of advanced/metastatic bone and soft tissue sarcomas still represents an unmet medical need. Recent advances in targeted therapies have highlighted the potential of cyclin-dependent kinases (CDK) inhibitors in several cancer types, including sarcomas. CDKs are master regulators o...

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Bibliographic Details
Main Authors: Alessandra Merlini, Valeria Pavese, Giulia Manessi, Martina Rabino, Francesco Tolomeo, Sandra Aliberti, Lorenzo D’Ambrosio, Giovanni Grignani
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
sarcoma
cyclin dependent kinases (CDK)
cdk inhibitors
target therapy
cell cycle
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1095219/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1095219/full

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