3449 Bacterial biotransformation of chemotherapeutics may promote diversity among the intestinal microbiota

OBJECTIVES/SPECIFIC AIMS: This study aims to test the hypothesis that bacterial biotransformation of chemotherapeutics promotes gut microbial diversity by enhancing persistence of drug-sensitive taxa. METHODS/STUDY POPULATION: The impacts of doxorubicin on a model community of gut bacteria was inves...

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Bibliographic Details
Main Authors: Ryan Andrew Blaustein, Patrick Casey Seed, Erica Marie Hartmann
Format: Article
Language:English
Published: Cambridge University Press 2019-03-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866119000116/type/journal_article