Bone Marrow Endothelial Cells Increase Prostate Cancer Cell Apoptosis in 3D Triculture Model of Reactive Stroma

The bone marrow tumor microenvironment (BMTE) is a complex network of cells, extracellular matrix, and sequestered signaling factors that initially act as a hostile environment for disseminating tumor cells (DTCs) from the cancerous prostate. Three-dimensional (3D) culture systems offer an opportuni...

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Bibliographic Details
Main Authors: Lindsey K. Sablatura, Tristen V. Tellman, Aemin Kim, Mary C. Farach-Carson
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/9/1271