Hydrogen-bonded organic framework biomimetic entrapment allowing non-native biocatalytic activity in enzyme

Abstract Nature programs the structural folding of an enzyme that allows its on-demand biofunctionality; however, it is still a long-standing challenge to manually modulate an enzyme’s conformation. Here, we design an exogenous hydrogen-bonded organic framework to modulate the conformation of cytoch...

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Bibliographic Details
Main Authors: Guosheng Chen, Linjing Tong, Siming Huang, Shuyao Huang, Fang Zhu, Gangfeng Ouyang
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32454-2