The presence of cerebellar B cell aggregates is associated with a specific chemokine profile in the cerebrospinal fluid in a mouse model of multiple sclerosis

The presence of cerebellar B cell aggregates is associated with a specific chemokine profile in the cerebrospinal fluid in a mouse model of multiple sclerosis

Abstract Background The presence of meningeal ectopic lymphoid structures (ELS) in a subgroup of patients diagnosed with secondary progressive multiple sclerosis (SPMS) corresponds to a pronounced cortical inflammation and an aggravated disease course. In MP4-induced experimental autoimmune encephal...

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Bibliographic Details
Main Authors: Verena Schropp, Rittika Chunder, Barbara Dietel, Sabine Tacke, Stefanie Kuerten
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Neuroinflammation
Subjects:
B cell aggregates
Chemokines
CSF
EAE
MP4
Online Access:https://doi.org/10.1186/s12974-023-02695-z

Internet

https://doi.org/10.1186/s12974-023-02695-z

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