Codon optimality has minimal effect on determining translation efficiency in mycobacterium tuberculosis

Abstract Mycobacterium tuberculosis (Mtb) is a slow-growing, intracellular pathogen that exhibits a high GC-rich genome. Several factors, including the GC content of the genome, influence the evolution of specific codon usage biases in genomes. As a result, the Mtb genome exhibits strong biases for...

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Bibliographic Details
Main Authors: Smitha Soman, Somdeb Chattopadhyay, Siya Ram, Vinay Kumar Nandicoori, G. Aneeshkumar Arimbasseri
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-27164-0