Repeated 5-aminolevulinic acid mediated sonodynamic therapy using magnetic resonance guided focused ultrasound in rat brain tumour models

Repeated 5-aminolevulinic acid mediated sonodynamic therapy using magnetic resonance guided focused ultrasound in rat brain tumour models

Abstract Sonodynamic therapy is an emerging therapeutic approach against brain tumours. However, the treatment scheme and ultrasound parameters have yet to be explored for clinical translation. Our study aimed to optimize ultrasound parameters for sonodynamic therapy (SDT) with 5-ALA as a sonosensit...

Full description

Bibliographic Details
Main Authors: Sheng-Kai Wu, Chia-Lin Tsai, Aisha Mir, Stuart L. Marcus, Kullervo Hynynen
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Sonodynamic therapy
5-Aminolevulinic acid
Brain tumour
MR-guided focused ultrasound
Burst length
Online Access:https://doi.org/10.1038/s41598-025-85314-6

Internet

https://doi.org/10.1038/s41598-025-85314-6

Similar Items