Wnt/β-Catenin Signaling Contributes to Paclitaxel Resistance in Bladder Cancer Cells with Cancer Stem Cell-Like Properties

Wnt/β-Catenin Signaling Contributes to Paclitaxel Resistance in Bladder Cancer Cells with Cancer Stem Cell-Like Properties

The Wnt/β-catenin pathway plays an important role in tumor progression and chemotherapy resistance and seems to be essential for the maintenance of cancer stem cells (CSC) in several tumor types. However, the interplay of these factors has not been fully addressed in bladder cancer. Here, our goal w...

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Bibliographic Details
Main Authors: Rocío Jiménez-Guerrero, Alejandro Belmonte-Fernández, M. Luz Flores, Mónica González-Moreno, Begoña Pérez-Valderrama, Francisco Romero, Miguel Á. Japón, Carmen Sáez
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
Wnt/β-catenin pathway
CSC phenotype
paclitaxel resistance
bladder cancer
Online Access:https://www.mdpi.com/1422-0067/23/1/450

Internet

https://www.mdpi.com/1422-0067/23/1/450

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