Novel anti-neuroinflammatory pyranone-carbamate derivatives as selective butyrylcholinesterase inhibitors for treating Alzheimer’s disease

Butyrylcholinesterase (BuChE) and neuroinflammation have recently emerged as promising therapeutic directions for Alzheimer’s disease (AD). Herein, we synthesised 19 novel pyranone-carbamate derivatives and evaluated their activities against cholinesterases and neuroinflammation. The optimal compoun...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Chuanyu Yu, Xueyan Liu, Bingxiang Ma, Jiexin Xu, Yiquan Chen, Chaoxian Dai, Huaping Peng, Daijun Zha
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Taylor & Francis Group 2024-12-01
Цуврал:Journal of Enzyme Inhibition and Medicinal Chemistry
Нөхцлүүд:
Онлайн хандалт:https://www.tandfonline.com/doi/10.1080/14756366.2024.2313682