Natural compounds targeting major cell signaling pathways: a novel paradigm for osteosarcoma therapy

Natural compounds targeting major cell signaling pathways: a novel paradigm for osteosarcoma therapy

Abstract Osteosarcoma is the most common primary bone cancer affecting children and adolescents worldwide. Despite an incidence of three cases per million annually, it accounts for an inordinate amount of morbidity and mortality. While the use of chemotherapy (cisplatin, doxorubicin, and methotrexat...

Full description

Bibliographic Details
Main Authors: Pablo Angulo, Gaurav Kaushik, Dharmalingam Subramaniam, Prasad Dandawate, Kathleen Neville, Katherine Chastain, Shrikant Anant
Format: Article
Language:English
Published: BMC 2017-01-01
Series:Journal of Hematology & Oncology
Subjects:
Osteosarcoma
Signaling pathways
Natural compounds
Ezrin
Online Access:http://link.springer.com/article/10.1186/s13045-016-0373-z

Internet

http://link.springer.com/article/10.1186/s13045-016-0373-z

Similar Items