Bilayer osteochondral graft in rabbit xenogeneic transplantation model comprising sintered 3D-printed bioceramic and human adipose-derived stem cells laden biohydrogel

Bilayer osteochondral graft in rabbit xenogeneic transplantation model comprising sintered 3D-printed bioceramic and human adipose-derived stem cells laden biohydrogel

Abstract Reconstruction of severe osteochondral defects in articular cartilage and subchondral trabecular bone remains a challenging problem. The well-integrated bilayer osteochondral graft design expects to be guided the chondrogenic and osteogenic differentiation for stem cells and provides a prom...

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Bibliographic Details
Main Authors: Chih-Yun Lee, Swathi Nedunchezian, Sung-Yen Lin, Yu-Feng Su, Che-Wei Wu, Shun-Cheng Wu, Chung-Hwan Chen, Chih-Kuang Wang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Biological Engineering
Subjects:
Osteochondral
Tissue engineering
Bioceramic scaffold
Digital light processing
Hyaluronic acid methacryloyl
Gelatin methacryloyl
Online Access:https://doi.org/10.1186/s13036-023-00389-x

Internet

https://doi.org/10.1186/s13036-023-00389-x

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