Efficient Synthesis of Isoquinoline Derivatives through Sequential Cyclization–Deoxygenation Reaction of 2-Alkynylbenzaldoximes

Efficient Synthesis of Isoquinoline Derivatives through Sequential Cyclization–Deoxygenation Reaction of 2-Alkynylbenzaldoximes

We describe a novel, simple, robust, and efficient cyclization/deoxygenation approach for the synthesis of functionalized isoquinoline derivatives. Over the course of continued studies on o-alkynylbenzaldoxime cyclization reactions, the formation of cyclic nitrones through 6-endo-dig cyclization was...

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Bibliographic Details
Main Authors: Mojtaba Ayoubi, Ali Nikbakht, Kamran Amiri, Alireza Abbasi Kejani, Hossein Zahedian Tejeneki, Saeed Balalaie
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2022-01-01
Series:SynOpen
Subjects:
2-alkynylbenzaldoxime
cyclization/deoxygenation
isoquinoline
silver triflate
bromine
carbon disulfide
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1719870

Internet

http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1719870

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