The tyrosine 73 and serine 83 dephosphorylation of H1N1 swine influenza virus NS1 protein attenuates virus replication and induces high levels of beta interferon

Abstract Background Nonstructural protein 1 (NS1) is a virulence factor encoded by influenza A virus (IAV) that is expressed in the nucleus and cytoplasm of host cells during the earliest stages of infection. NS1 is a multifunctional protein that plays an important role in virus replication, virulen...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jinghua Cheng, Jie Tao, Benqiang Li, Ying Shi, Huili Liu
التنسيق: مقال
اللغة:English
منشور في: BMC 2019-12-01
سلاسل:Virology Journal
الموضوعات:
الوصول للمادة أونلاين:https://doi.org/10.1186/s12985-019-1255-0