The tyrosine 73 and serine 83 dephosphorylation of H1N1 swine influenza virus NS1 protein attenuates virus replication and induces high levels of beta interferon

Abstract Background Nonstructural protein 1 (NS1) is a virulence factor encoded by influenza A virus (IAV) that is expressed in the nucleus and cytoplasm of host cells during the earliest stages of infection. NS1 is a multifunctional protein that plays an important role in virus replication, virulen...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Jinghua Cheng, Jie Tao, Benqiang Li, Ying Shi, Huili Liu
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: BMC 2019-12-01
Sraith:Virology Journal
Ábhair:
Rochtain ar líne:https://doi.org/10.1186/s12985-019-1255-0